Bepiastine

Bepiastine

SCHEMBL29560445

CN(C)CCN1C(=O)c2cccnc2Sc2ccccc21

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.64
KDM1A O60341 1/20 0.57
THRB P10828 2/20 0.55
DRD2 P14416 3/20 0.54
HTR6 P50406 3/20 0.54
SLC6A4 P31645 3/20 0.54
HRH1 P35367 3/20 0.54
MAPT P10636 2/20 0.54
HTR1A P08908 2/20 0.54
HTR2A P28223 2/20 0.54
HTR7 P34969 2/20 0.54
CHRM2 P08172 1/20 0.54
ADRA2A P08913 1/20 0.54
DRD1 P21728 1/20 0.54
SLC6A2 P23975 1/20 0.54
ADRA1A P35348 1/20 0.54
OPRM1 P35372 1/20 0.54
DRD3 P35462 1/20 0.54
TP53 P04637 3/20 0.54
POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bepiastine SCHEMBL1815039 1.00 LMNA (0.64) LMNAKDM1ATHRBDRD2HTR6
SCHEMBL9101155 0.84 LMNA (0.65) LMNATHRBMAPTTP53POLB
SCHEMBL9101431 0.79 LMNA (0.58) LMNATHRBMAPTTP53POLB
Fenethazine SCHEMBL29394568 0.74 KDM1A (1.00) LMNAKDM1ADRD2HTR6SLC6A4
Fenethazine SCHEMBL144367 0.74 KDM1A (1.00) LMNAKDM1ADRD2HTR6SLC6A4
Fenethazine SCHEMBL662746 0.73 KDM1A (0.96) LMNAKDM1ADRD2HTR6SLC6A4
SCHEMBL9833656 0.72 CYP2D6 (0.66) LMNAKDM1ADRD2HTR6SLC6A4
SCHEMBL11747930 0.72 DRD2 (0.69) LMNAKDM1ADRD2HTR6SLC6A4
SCHEMBL11745375 0.72 HRH1 (0.61) LMNAKDM1ADRD2HTR6SLC6A4
Dibenzepin SCHEMBL14973430 0.71 HRH1 (0.94) LMNAKDM1ADRD2HTR6SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924867-A Polypropylene composite material with high surface hardness and preparation method thereof 苏州润佳高分子材料有限公司 2024-04-26 CN claimed
EP-3609579-B1 ANTIMICROBIAL COMPOUNDS FROM THE GENUS DELFTIA MINI OF HEALTH STATE OF ISRAEL (IL) 2025-01-01 EP disclosed
CN-118063923-B High-temperature-resistant high-flame-retardance low-smoke halogen-free thermoplastic plastic and preparation method and application thereof 广州敬信高聚物科技有限公司 2024-10-11 CN disclosed
CN-118272019-A Conductive silver adhesive, preparation method and application thereof and power device 北京中科纳通电子技术有限公司 2024-07-02 CN disclosed
CN-118063923-A High-temperature-resistant high-flame-retardance low-smoke halogen-free thermoplastic plastic and preparation method and application thereof 广州敬信高聚物科技有限公司 2024-05-24 CN disclosed
CN-117924867-A Polypropylene composite material with high surface hardness and preparation method thereof 苏州润佳高分子材料有限公司 2024-04-26 CN disclosed
CN-116715924-A Polyvinyl chloride high-foaming material and mould pressing foaming production method and application thereof 新疆天创科技有限责任公司 2023-09-08 CN disclosed
CN-115918244-A First node, second node and method performed thereby for handling packet duplication in a multihop network 瑞典爱立信有限公司 2023-04-04 CN disclosed
CN-115087488-A Antibodies and fusion proteins binding to CCR8 and uses thereof 震动疗法股份有限公司 2022-09-20 CN disclosed
EP-3983431-A1 DIAGNOSTICS AND TREATMENTS BASED UPON MOLECULAR CHARACTERIZATION OF COLORECTAL CANCER The Board of Trustees of the Leland Stanford Junior University (US) 2022-04-20 EP disclosed