Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11865541 | 0.87 | PBRM1 (0.66) | PBRM1NPC1POLBMITFLMNA | |
| SCHEMBL9719372 | 0.83 | PBRM1 (0.70) | PBRM1NPC1POLBMITFLMNA | |
| SCHEMBL9099918 | 0.83 | PLK1 (0.55) | NPC1POLBLMNACA2THRB | |
| SCHEMBL9097509 | 0.83 | PBRM1 (0.88) | PBRM1NPC1POLBMITFLMNA | |
| SCHEMBL203373 | 0.83 | PBRM1 (0.88) | PBRM1NPC1POLBMITFLMNA | |
| SCHEMBL29492473 | 0.83 | PBRM1 (0.88) | PBRM1NPC1POLBMITFLMNA | |
| SCHEMBL21887389 | 0.83 | L3MBTL1 (0.53) | CA1CA2CA9CNR2GAA | |
| Benzophenone SCHEMBL28417175 | 0.81 | L3MBTL1 (0.58) | NPC1POLBLMNATHRBCNR2 | |
| SCHEMBL4605419 | 0.81 | L3MBTL1 (0.58) | NPC1POLBLMNATHRBCNR2 | |
| SCHEMBL8079282 | 0.81 | GAA (0.50) | NPC1LMNATHRBCNR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510425-A | AROMATIC POLYIMIDE-EPOXY COPOLYMER MODIFIED BY BISMALEIMIDE COMPOUND; FLEXIBILITY, PEELING STRENGTH; COLDSETTING RESINS, ADHESIVES | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1996-04-23 | — | — | US | disclosed |