SCHEMBL9719372

SCHEMBL9719372

Nc1cccc(C(=O)c2ccc(Cc3ccc(C(=O)c4cccc(N)c4)cc3)cc2)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.70
LMNA P02545 2/20 0.60
NPC1 O15118 1/20 0.60
MITF O75030 1/20 0.60
POLB P06746 1/20 0.60
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA9 Q16790 2/20 0.56
ATM Q13315 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
SRD5A2 P31213 2/20 0.46
PLA2G10 O15496 1/20 0.46
PLA2G2A P14555 1/20 0.46
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MPO P05164 1/20 0.43
F2 P00734 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9719354 0.97 PBRM1 (0.66) PBRM1LMNANPC1MITFPOLB
SCHEMBL9719358 0.95 PBRM1 (0.64) PBRM1LMNANPC1MITFPOLB
SCHEMBL203373 0.89 PBRM1 (0.88) PBRM1LMNANPC1MITFPOLB
SCHEMBL29492473 0.89 PBRM1 (0.88) PBRM1LMNANPC1MITFPOLB
SCHEMBL9097509 0.89 PBRM1 (0.88) PBRM1LMNANPC1MITFPOLB
SCHEMBL9719321 0.86 CYP19A1 (0.53) PBRM1LMNANPC1MITFPOLB
SCHEMBL11865541 0.86 PBRM1 (0.66) PBRM1LMNANPC1MITFPOLB
SCHEMBL127545 0.85 PBRM1 (0.81) PBRM1LMNANPC1MITFPOLB
SCHEMBL5832368 0.85 PBRM1 (0.81) PBRM1LMNANPC1MITFPOLB
SCHEMBL5114913 0.85 PBRM1 (0.81) PBRM1LMNANPC1MITFPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5153277-A Curable mixture comprising amino group-containing unsaturated ester compound or amino resin or polyethers and epoxy compound , curing agent; heat resistance, workability, adhesiveness to reinforcing fibers, fatigue-resistance NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1992-10-06 US disclosed
US-4980416-A HEAT RESISTANCE, NONCRACKING, HIGH STRENGTH NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1990-12-25 US disclosed
US-4837280-A ACRYLATE GROUP-CONTAINING POLYAROMATIC AMINE COMPOUNDS TO FORM THERMOSETTING RESINS; HEAT RESISTANCE NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1989-06-06 US disclosed