Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014933 | 0.90 | TRPA1 (0.53) | TRPA1ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL7020545 | 0.84 | ALDH1A1 (0.48) | TRPA1ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL8911595 | 0.82 | POLB (0.46) | TRPA1ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL7021611 | 0.80 | RAB9A (0.56) | TRPA1ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL7381841 | 0.76 | GRIN1 (0.55) | ALDH1A1CYP1A2HPGDMEN1KMT2A | |
| SCHEMBL7019918 | 0.74 | GAA (0.54) | TRPA1ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL7020541 | 0.73 | TRPA1 (0.50) | TRPA1ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL14665633 | 0.73 | CYP3A4 (0.55) | ALDH1A1CYP1A2CYP3A4HSD17B10HPGD | |
| SCHEMBL627763 | 0.72 | QPCT (0.62) | TRPA1ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL8911589 | 0.72 | TRPA1 (0.48) | TRPA1ALDH1A1CYP1A2CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459705-A1 | PRODUCTION OF ß-CELLS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2012-06-06 | — | — | EP | disclosed |