Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | P4HB | P07237 | 12/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795707 | 0.84 | PDCD1 (0.49) | P4HBFBP1MAOAMAOBPDCD1 | |
| SCHEMBL7429846 | 0.82 | GRIK1 (0.49) | TBXAS1P4HBFBP1TOP1 | |
| SCHEMBL7429849 | 0.82 | GRIK1 (0.49) | TBXAS1P4HBFBP1TOP1 | |
| SCHEMBL6795706 | 0.82 | PDCD1 (0.50) | P4HBFBP1MAOAMAOBPDCD1 | |
| SCHEMBL921088 | 0.80 | FBP1 (0.48) | P4HBFBP1PDCD1CD274 | |
| SCHEMBL712359 | 0.80 | FBP1 (0.48) | P4HBFBP1PDCD1CD274 | |
| SCHEMBL712358 | 0.80 | FBP1 (0.48) | P4HBFBP1PDCD1CD274 | |
| SCHEMBL1363095 | 0.78 | TBXAS1 (0.62) | TBXAS1MAOBTOP1 | |
| SCHEMBL8798110 | 0.78 | TBXAS1 (0.62) | TBXAS1MAOBTOP1 | |
| SCHEMBL2379927 | 0.78 | TBXAS1 (0.62) | TBXAS1MAOBTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5481021-A | Phenyl amidines derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0574545-B1 | PHENYL AMIDINES DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1994-11-30 | — | — | EP | disclosed |
| EP-0574545-A1 | PHENYL AMIDINES DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS. | SEARLE & CO (US) | 1993-12-22 | — | — | EP | disclosed |
| WO-1992015607-A2 | PHENYL AMIDINES DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-09-17 | — | — | WO | disclosed |