SCHEMBL9101408

SCHEMBL9101408

O=[N+]([O-])c1c(C2CCCCC2)cccc1S(=O)(=O)O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.43
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
PTGS2 P35354 1/20 0.39
EPHX2 P34913 1/20 0.35
ALDH1A1 P00352 3/20 0.35
ACHE P22303 1/20 0.35
MAPT P10636 2/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
MCOLN3 Q8TDD5 1/20 0.34
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SLC18A3 Q16572 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9101776 0.93 HSD11B1 (0.37) HSP90AA1KMT2AMEN1ALDH1A1ACHE
SCHEMBL9098064 0.90 ACHE (0.36) HSP90AA1KMT2AMEN1ALDH1A1ACHE
SCHEMBL28163931 0.86 HSP90AA1 (0.43) HSP90AA1KMT2AMEN1PTGS2ALDH1A1
SCHEMBL9101961 0.84 HSD11B1 (0.38) KMT2AMEN1ALDH1A1ACHEMAPT
SCHEMBL9101914 0.82 KMT2A (0.34) HSP90AA1KMT2AMEN1EPHX2ALDH1A1
SCHEMBL9100928 0.81 ACHE (0.37) KMT2AMEN1EPHX2ALDH1A1ACHE
SCHEMBL4279326 0.78 PTGS2 (0.46) PTGS2ALDH1A1MAPTPTGDR2
SCHEMBL28325802 0.78 CA2 (0.38) KMT2AMEN1ALDH1A1MAPT
SCHEMBL10408635 0.77 PTGS2 (0.40) PTGS2PTGDR2
SCHEMBL9099696 0.77 KMT2A (0.48) KMT2AMEN1EPHX2ALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489501-A MIXTURES OF TWO COORDINATION COMPOUNDS WHICH REACT TO FORM NEW COORDINATION COMPOUND WHILE CAUSING VISIBLE COLOR CHANGES RICOH COMPANY, LTD. (JP) 1996-02-06 US disclosed