Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.64 |
| ▸ | NAALAD2 | Q9Y3Q0 | 5/20 | 0.64 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.64 |
| ▸ | GNPAT | O15228 | 1/20 | 0.46 |
| ▸ | GGH | Q92820 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910360 | 1.00 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL910174 | 1.00 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL910273 | 1.00 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL910607 | 0.98 | FOLH1 (0.62) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Hydrochloric Acid SCHEMBL910549 | 0.98 | FOLH1 (0.62) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Succinic Acid SCHEMBL911170 | 0.96 | FOLH1 (0.60) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Oxalic Acid SCHEMBL910834 | 0.96 | FOLH1 (0.60) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Acetic Acid SCHEMBL910582 | 0.94 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Sulfuric Acid SCHEMBL910205 | 0.93 | FOLH1 (0.56) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Maleic Acid SCHEMBL910784 | 0.91 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGNPATCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110004019-A1 | Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | claimed |
| EP-2255780-A1 | PARAKERATOSIS INHIBITOR, PORE SHRINKING AGENT OR AGENT FOR PREVENTING OR IMPROVING ROUGH SKIN, AND COMPOSITION FOR EXTERNAL USE ON THE SKIN CONTAINING THE SAME | Shiseido Company, Ltd. (JP) | 2010-12-01 | — | — | EP | claimed |
| US-20240336654-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | Universität Zürich (CH) | 2024-10-10 | — | — | US | disclosed |
| US-20240228555-A9 | ANTIMICROBIAL PEPTIDOMIMETICS | BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH) | 2024-07-11 | — | — | US | disclosed |
| EP-4380689-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | Basilea Pharmaceutica International AG, Allschwil (CH) | 2024-06-12 | — | — | EP | disclosed |
| CN-118043339-A | Antimicrobial peptidomimetics | 巴斯利尔药物阿尔施维尔国际股份公司 | 2024-05-14 | — | — | CN | disclosed |
| US-20240132553-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | SPEXIS AG (CH) | 2024-04-25 | — | — | US | disclosed |
| US-20230295234-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | SPEXIS AG (CH) | 2023-09-21 | — | — | US | disclosed |
| EP-4214220-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | Spexis AG (CH) | 2023-07-26 | — | — | EP | disclosed |
| EP-4214221-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | Spexis AG (CH) | 2023-07-26 | — | — | EP | disclosed |
| CN-115989237-A | Antimicrobial peptidomimetics | 斯派西斯公司 | 2023-04-18 | — | — | CN | disclosed |
| JP-2009242249-A | PARAKERATOSIS INHIBITOR AND PORE SHRINKING AGENT | SHISEIDO CO LTD | 2009-10-22 | — | — | JP | disclosed |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | FOLH1 1320/4885NAALAD2 3887/4885RIMKLA 924/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | FOLH1 2199/4885NAALAD2 4232/4885RIMKLA 2209/4885 |
| US-20110004019-A1 | Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same | CUTA, GLRA3, ARGLU1 | FOLH1 4099/4885NAALAD2 1692/4885RIMKLA 881/4885 |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | KRT18, INHA, H1-5 | FOLH1 2438/4885NAALAD2 4150/4885RIMKLA 1701/4885 |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | BHMT, KRT18, INMT | FOLH1 647/4885NAALAD2 1661/4885RIMKLA 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.