Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14012481 | 0.90 | PBRM1 (0.53) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL29492473 | 0.86 | PBRM1 (0.88) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL9097509 | 0.86 | PBRM1 (0.88) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL203373 | 0.86 | PBRM1 (0.88) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL127545 | 0.82 | PBRM1 (0.81) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL5832368 | 0.82 | PBRM1 (0.81) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL17744847 | 0.82 | PBRM1 (0.81) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL5114913 | 0.82 | PBRM1 (0.81) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL29037240 | 0.82 | PBRM1 (0.81) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL8762167 | 0.82 | SRD5A2 (0.52) | NPC1LMNAPOLBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553612-B1 | Polyimides, thermosetting resin compositions containing the polyimides, formed articles of the resin compositions, and production process of the polyimides | HITACHI CHEMICAL CO LTD (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5508357-A | SOLUBILITY IN SOLVENT, LOW MELTING POINT | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1996-04-16 | — | — | US | disclosed |