SCHEMBL9101840

SCHEMBL9101840

CC=CC=CC(=O)OC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CYP19A1 P11511 4/20 0.35
THRB P10828 2/20 0.34
CYP2C9 P11712 1/20 0.34
ALDH1A1 P00352 3/20 0.34
GLA P06280 1/20 0.34
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP17A1 P05093 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CA2 P00918 1/20 0.33
EDNRA P25101 3/20 0.33
EPHX2 P34913 1/20 0.32
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9101834 1.00 NAAA (0.39) NAAANPSR1CYP19A1THRBCYP2C9
SCHEMBL1337905 0.87 NPSR1 (0.42) NAAANPSR1CYP19A1THRBCYP2C9
SCHEMBL1337900 0.87 NPSR1 (0.42) NAAANPSR1CYP19A1THRBCYP2C9
SCHEMBL9274200 0.83 THRB (0.44) NAAANPSR1CYP19A1THRBCYP2C9
SCHEMBL7536676 0.83 THRB (0.44) NAAANPSR1CYP19A1THRBCYP2C9
SCHEMBL2307504 0.83 THRB (0.44) NAAANPSR1CYP19A1THRBCYP2C9
SCHEMBL547983 0.80 NAAA (0.44) NAAANPSR1CYP19A1THRBCYP2C9
SCHEMBL15082436 0.79 NAAA (0.43) NAAANPSR1CYP19A1ALDH1A1GLA
SCHEMBL1615681 0.78 NAAA (0.40) NAAANPSR1CYP19A1THRBCYP2C9
SCHEMBL23827187 0.77 NPSR1 (0.36) NAAANPSR1THRBCYP2C9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10889146-B2 Tire object provided with an elastomer layer made of a thermoplastic elastomer in the form of an (A-b-(a-methylstyrene-co-B))n-b-C block copolymer COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-01-12 US disclosed
CN-104812790-B Organopolysiloxane graft polymers 花王株式会社 2019-04-12 CN disclosed
EP-2927253-B1 ORGANOPOLYSILOXANE GRAFT POLYMER KAO CORP (JP) 2018-09-12 EP disclosed
US-10030131-B2 Pneumatic object provided with a gastight layer containing a thermoplastic elastomer and a thermoplastic COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-07-24 US disclosed
US-9914328-B2 Inflatable object provided with a gas-tight layer containing a thermoplastic elastomer and a hydrocarbon-based resin COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (CH) 2018-03-13 US disclosed
US-20180043734-A1 TIRE OBJECT PROVIDED WITH AN ELASTOMER LAYER MADE OF A THERMOPLASTIC ELASTOMER IN THE FORM OF AN (A-B-(A-METHYLSTYRENE-CO-B))N-B-C BLOCK COPOLYMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-02-15 US disclosed
US-9351920-B2 Organopolysiloxane graft polymer KAO CORPORATION (JP) 2016-05-31 US disclosed
US-20150297498-A1 ORGANOPOLYSILOXANE GRAFT POLYMER KAO CORPORATION (JP) 2015-10-22 US disclosed
US-20150290975-A1 PNEUMATIC TIRE WITH AN INNER LINER BONDED BY A FIBRE ASSEMBLY COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-10-15 US disclosed
EP-2927253-A1 ORGANOPOLYSILOXANE GRAFT POLYMER Kao Corporation (JP) 2015-10-07 EP disclosed
US-20140343216-A1 TIRE PROVIDED WITH AN INNER LAYER COMPRISING A MIXTURE OF A DIENE ELASTOMER AND A THERMOPLASTIC ELASTOMER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2014-11-20 US disclosed
US-20140343190-A1 TIRE PROVIDED WITH A TREAD MADE FROM A MIXTURE OF A DIENE ELASTOMER AND A THERMOPLASTIC ELASTOMER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2014-11-20 US disclosed
US-20140299249-A1 TIRE PROVIDED WITH AN OUTER SIDEWALL COMPRISING A MIXTURE OF A DIENE ELASTOMER AND A THERMOPLASTIC ELASTOMER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2014-10-09 US disclosed
US-20130209716-A1 INFLATABLE ARTICLE PROVIDED WITH GAS-IMPERMEABLE LAYER BASED ON A BLEND OF A BUTYL RUBBER AND A THERMOPLASTIC ELASTOMER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2013-08-15 US disclosed
US-20130196086-A1 INFLATABLE OBJECT PROVIDED WITH A GAS-TIGHT LAYER CONTAINING A THERMOPLASTIC ELASTOMER AND A HYDROCARBON-BASED RESIN MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2013-08-01 US disclosed
US-20130168001-A1 PNEUMATIC OBJECT PROVIDED WITH A GAS-TIGHT LAYER COMPRISING A MIXTURE OF A THERMOPLASTIC ELASTOMER AND A BUTYL RUBBER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2013-07-04 US disclosed
US-20130072621-A1 PNEUMATIC OBJECT PROVIDED WITH A GASTIGHT LAYER CONTAINING A THERMOPLASTIC ELASTOMER AND A THERMOPLASTIC MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2013-03-21 US disclosed
US-20120315408-A1 INFLATABLE ARTICLE PROVIDED WITH A GASTIGHT LAYER BASED ON A BLEND OF A THERMOPLASTIC ELASTOMER AND OF A PARTIALLY CROSSLINKED BUTYL RUBBER. MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2012-12-13 US disclosed
US-20120149822-A1 PNEUMATIC OBJECT PROVIDED WITH A GASTIGHT LAYER MADE OF A THERMOPLASTIC ELASTOMER AND LAMELLAR FILLER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2012-06-14 US disclosed
US-20120141696-A1 ELASTOMER COMPOSITION MADE FROM A THERMOPLASTIC COPOLYMER, INFLATABLE OBJECT PROVIDED WITH A GAS BARRIER MADE FROM SUCH A COMPOSITION SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150297498-A1 ORGANOPOLYSILOXANE GRAFT POLYMER IDUA, PIGS, GMNN NAAA 3078/4885NPSR1 1221/4885CYP19A1 4318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.