Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852541 | 0.85 | LMNA (0.61) | LMNASMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL8773948 | 0.81 | LMNA (0.58) | LMNASMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL8230945 | 0.81 | LMNA (0.53) | LMNASMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL5682572 | 0.80 | LMNA (0.56) | LMNASMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL8773943 | 0.80 | LMNA (0.56) | LMNASMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL10875389 | 0.79 | LMNA (0.68) | LMNASMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL332859 | 0.79 | LMNA (0.54) | LMNASMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL9413251 | 0.79 | LMNA (0.54) | LMNASMN1; SMN2CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL22680970 | 0.78 | LMNA (0.68) | LMNASMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL9016334 | 0.77 | LMNA (0.53) | LMNASMN1; SMN2KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543133-A | PREPARING PREMIX OF CONTRAST AGENT AND SURFACTANT; REDUCTION OF PARTICLE SIZE | NANOSYSTEMS L.L.C. (US) | 1996-08-06 | — | — | US | disclosed |