Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 5/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103626 | 0.94 | GRIA2 (0.40) | GRIA2PDK1PDK2PDK3PDK4 | |
| SCHEMBL9100243 | 0.90 | THRB (0.34) | BCHEHDAC3HDAC1HDAC6CYP2D6 | |
| SCHEMBL9100816 | 0.89 | HDAC1 (0.33) | BCHEHDAC3HDAC1HDAC6CYP2D6 | |
| SCHEMBL9099076 | 0.89 | RORB (0.35) | BCHEHDAC3HDAC1HDAC6CYP2D6 | |
| SCHEMBL9104426 | 0.88 | HDAC6 (0.35) | BCHEHDAC3HDAC1HDAC6MAPT | |
| SCHEMBL9103457 | 0.87 | GRIA2 (0.34) | GRIA2HDAC3HDAC1HDAC6TSHR | |
| SCHEMBL9103620 | 0.86 | HDAC3 (0.33) | BCHEHDAC3HDAC1HDAC6MAPT | |
| SCHEMBL9102352 | 0.84 | GRIA2 (0.31) | GRIA2PDK1PDK2PDK3PDK4 | |
| SCHEMBL9102741 | 0.82 | GRIA2 (0.38) | GRIA2PDK1PDK2PDK3PDK4 | |
| SCHEMBL9103994 | 0.82 | LMNA (0.36) | BCHEHDAC3HDAC1HDAC6CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |