Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.46 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.46 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.43 |
| ▸ | GNPAT | O15228 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetylglutamic Acid SCHEMBL910770 | 1.00 | FOLH1 (0.46) | FOLH1NAALAD2RIMKLAITGB3ITGA2B | |
| Acetylglutamic Acid SCHEMBL910067 | 1.00 | FOLH1 (0.46) | FOLH1NAALAD2RIMKLAITGB3ITGA2B | |
| Aceglumate SCHEMBL910345 | 0.99 | FOLH1 (0.47) | FOLH1NAALAD2RIMKLAITGB3ITGA2B | |
| Acetylglutamic Acid SCHEMBL910789 | 0.99 | FOLH1 (0.47) | FOLH1NAALAD2RIMKLAITGB3ITGA2B | |
| Acetylglutamic Acid SCHEMBL910760 | 0.99 | FOLH1 (0.47) | FOLH1NAALAD2RIMKLAITGB3ITGA2B | |
| Acetylglutamic Acid SCHEMBL716411 | 0.80 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGNPATKDM4E | |
| Aceglumate SCHEMBL198970 | 0.80 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGNPATKDM4E | |
| Acetylglutamic Acid SCHEMBL82128 | 0.80 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGNPATKDM4E | |
| Acetylglutamic Acid SCHEMBL2512801 | 0.80 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGNPATKDM4E | |
| SCHEMBL1604394 | 0.79 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110004019-A1 | Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2255780-A1 | PARAKERATOSIS INHIBITOR, PORE SHRINKING AGENT OR AGENT FOR PREVENTING OR IMPROVING ROUGH SKIN, AND COMPOSITION FOR EXTERNAL USE ON THE SKIN CONTAINING THE SAME | Shiseido Company, Ltd. (JP) | 2010-12-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110004019-A1 | Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same | CUTA, GLRA3, ARGLU1 | FOLH1 4099/4885NAALAD2 1692/4885RIMKLA 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.