Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.72 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199132 | 0.88 | CA9 (0.80) | CA9CHRNA7FAAHPTGS1HTT | |
| SCHEMBL9207779 | 0.85 | CA9 (0.75) | CA9CHRNA7FAAHPTGS1HTT | |
| SCHEMBL16876845 | 0.85 | FAAH (0.58) | CA9CHRNA7FAAHPTGS1PTGS2 | |
| SCHEMBL8536452 | 0.85 | CA9 (0.57) | CA9CHRNA7PTGS1PTGS2CYP2C9 | |
| SCHEMBL9203320 | 0.84 | CA9 (0.84) | CA9CHRNA7FAAHPTGS1HTT | |
| SCHEMBL9210890 | 0.84 | CA9 (0.74) | CA9CHRNA7FAAHPTGS1HTT | |
| SCHEMBL17077244 | 0.84 | ILK (0.52) | CA9CHRNA7PTGS1HTTL3MBTL1 | |
| SCHEMBL17077240 | 0.79 | PTGS1 (0.80) | PTGS1PTGS2CYP2C9 | |
| SCHEMBL2916210 | 0.79 | CHRNA7 (0.52) | CA9CHRNA7FAAHPTGS1PTGS2 | |
| SCHEMBL16876837 | 0.78 | FAAH (0.58) | CA9CHRNA7FAAHPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2642856-B1 | INTEGRIN-LINKED KINASE INHIBITORS | UNIV OHIO STATE RES FOUND (US) | 2017-07-19 | — | — | EP | disclosed |
| US-9457031-B2 | Antibacterial protein kinase inhibitors | OHIO STATE INNOVATION FOUNDATION | 2016-10-04 | — | — | US | disclosed |
| US-20150258100-A1 | ANTIBACTERIAL PROTEIN KINASE INHIBITORS | OHIO STATE INNOVATION FOUNDATION | 2015-09-17 | — | — | US | disclosed |
| US-8658647-B2 | Integrin-linked kinase inhibitors | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2014-02-25 | — | — | US | disclosed |
| US-20120142702-A1 | INTEGRIN-LINKED KINASE INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142702-A1 | INTEGRIN-LINKED KINASE INHIBITORS | PTK2, ITGB1, ITGB2 | CA9 2026/4885CHRNA7 1521/4885FAAH 4790/4885 |
| US-20150258100-A1 | ANTIBACTERIAL PROTEIN KINASE INHIBITORS | DMPK, MYLK3, MYLK2 | CA9 3875/4885CHRNA7 4540/4885FAAH 2732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.