Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762406 | 0.87 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TAS1R3TAS1R1F10 | |
| SCHEMBL9099363 | 0.78 | MEN1 (0.43) | ALDH1A1TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL1429905 | 0.76 | HSD17B10 (0.46) | ALDH1A1HSD17B10TAS1R3TAS1R1F10 | |
| SCHEMBL15135175 | 0.75 | HSD17B1 (0.47) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL6117322 | 0.75 | HTR2A (0.43) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL6117811 | 0.74 | HSD17B10 (0.39) | ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL6117367 | 0.74 | PPM1D (0.48) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24254051 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TAS1R3TAS1R1F10 | |
| SCHEMBL7978840 | 0.72 | KMT2A (0.49) | ALDH1A1HSD17B10F10MEN1KMT2A | |
| SCHEMBL6117229 | 0.72 | RAB9A (0.61) | ALDH1A1F10MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460791-A1 | INDOLE DERIVATIVE AND PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-06-06 | — | — | EP | disclosed |