Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.43 |
| ▸ | XIAP | P98170 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 5/20 | 0.35 |
| ▸ | F3 | P13726 | 5/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 3/20 | 0.33 |
| ▸ | ACE | P12821 | 3/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106413 | 0.93 | GHSR (0.41) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL9107930 | 0.91 | GHSR (0.44) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL9102884 | 0.88 | GHSR (0.55) | GHSRXIAPAGTR1 | |
| SCHEMBL9103074 | 0.87 | GHSR (0.44) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL9108492 | 0.86 | GHSR (0.52) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL7785751 | 0.86 | GHSR (0.45) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL9109384 | 0.86 | GHSR (0.40) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL9109388 | 0.86 | GHSR (0.40) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL7791984 | 0.85 | GHSR (0.50) | GHSRXIAPAGTR1F7F3 | |
| SCHEMBL9108493 | 0.84 | XIAP (0.42) | GHSRXIAPAGTR1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430144-A | E.g, N-(1-((2'-((methoxycarbonyl)amino)(1,1'-biphenyl)-4-yl) methyl)-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-3-yl)-3 ((fur-2-yl)methyl)amino-3-methylbutanamide | MERCK & CO., INC. (US) | 1995-07-04 | — | — | US | disclosed |