Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14688168 | 0.90 | ABCB1 (0.43) | ABCB1MAPTPOLBNPC1RAB9A | |
| SCHEMBL2482845 | 0.89 | ABCB1 (0.51) | ABCB1NPC1RAB9A | |
| SCHEMBL5053940 | 0.83 | ABCB1 (0.64) | ABCB1 | |
| SCHEMBL17416625 | 0.82 | ABCB1 (0.52) | ABCB1NPC1RAB9A | |
| SCHEMBL9232983 | 0.81 | ABCB1 (0.48) | ABCB1NPC1RAB9A | |
| SCHEMBL9101226 | 0.79 | ABCB1 (0.47) | ABCB1NPC1RAB9A | |
| SCHEMBL17416629 | 0.78 | CTSD (0.43) | NPC1RAB9APDE2ALMNA | |
| SCHEMBL18091865 | 0.78 | NPC1 (0.48) | ABCB1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL9100311 | 0.78 | RAB9A (0.43) | ABCB1MAPTNPC1RAB9ALMNA | |
| SCHEMBL17416624 | 0.77 | ABCB1 (0.53) | ABCB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463269-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |