SCHEMBL9105223

SCHEMBL9105223

CCc1cccc2c1Oc1cccc(CC)c1N2CCCS(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.37
MEN1 O00255 4/20 0.37
POLB P06746 4/20 0.37
KMT2A Q03164 4/20 0.37
MMP13 P45452 4/20 0.37
HPGD P15428 4/20 0.35
TDP1 Q9NUW8 4/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPK1 P28482 3/20 0.35
ALPG P10696 2/20 0.35
ALOX15 P16050 3/20 0.34
ALOX12 P18054 2/20 0.34
CASP1 P29466 2/20 0.34
HSD17B10 Q99714 2/20 0.34
PKM P14618 1/20 0.34
LMNA P02545 1/20 0.34
CASP7 P55210 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9103557 0.90 MEN1 (0.39) MAPTMEN1POLBKMT2AMMP13
SCHEMBL9102942 0.90 MAPT (0.35) MAPTMEN1POLBKMT2AMMP13
SCHEMBL9101924 0.89 MEN1 (0.40) MAPTMEN1POLBKMT2AMMP13
SCHEMBL9105933 0.89 MAPT (0.36) MAPTMEN1POLBKMT2AMMP13
SCHEMBL9102674 0.89 MTNR1A (0.35) MAPTMEN1POLBKMT2AMMP13
SCHEMBL9105470 0.88 MAPT (0.32) MAPTMEN1POLBKMT2AMMP13
SCHEMBL9103483 0.83 MAPT (0.34) MAPTMEN1POLBKMT2AMMP13
SCHEMBL9101949 0.82 SIGMAR1 (0.38) MAPTMEN1POLBKMT2AMMP13
SCHEMBL9106521 0.82 MEN1 (0.34) MAPTMEN1POLBKMT2AMMP13
SCHEMBL9105392 0.81 ALDH1A1 (0.35) MAPTMEN1POLBKMT2AMMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed