Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107920 | 0.93 | ACHE (0.54) | ACHEKMT2ANPSR1MEN1KDM1A | |
| SCHEMBL9351793 | 0.85 | KDM1A (0.45) | ACHEKMT2ANPSR1BCHEKDM1A | |
| SCHEMBL9105519 | 0.85 | ACHE (0.47) | ACHEKMT2ANPSR1BCHEKDM1A | |
| SCHEMBL9107670 | 0.84 | ACHE (0.61) | ACHEKMT2ABCHEMEN1KDM1A | |
| SCHEMBL9351852 | 0.80 | ACHE (0.46) | ACHEKMT2ABCHEKDM1AHTT | |
| SCHEMBL9108831 | 0.80 | ACHE (0.60) | ACHEBCHEKDM1A | |
| SCHEMBL9107818 | 0.77 | ACHE (0.71) | ACHEBCHEKDM4EHTTPOLB | |
| SCHEMBL9109989 | 0.77 | KDM4E (0.39) | ACHEKMT2ANPSR1BCHEMEN1 | |
| SCHEMBL9108871 | 0.76 | KDM1A (0.57) | ACHEKMT2ANPSR1BCHEMEN1 | |
| SCHEMBL9108799 | 0.74 | ACHE (0.55) | ACHEKMT2ANPSR1BCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897400-A | ENHANCING MEMORY | HOESCHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-01-30 | — | — | US | claimed |
| US-5401749-A | Memory enhancers, cholinergic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-03-28 | — | — | US | disclosed |
| US-4897400-A | ENHANCING MEMORY | HOESCHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-01-30 | — | — | US | disclosed |