Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9105577 | 0.93 | ACHE (0.52) | ACHEKMT2ANPSR1MEN1KDM1A | |
| SCHEMBL9109989 | 0.84 | KDM4E (0.39) | ACHEKMT2ANPSR1MEN1KDM1A | |
| SCHEMBL9108871 | 0.84 | KDM1A (0.57) | ACHEKMT2ANPSR1MEN1KDM1A | |
| SCHEMBL9106918 | 0.79 | ACHE (0.55) | ACHEKDM1A | |
| SCHEMBL9351828 | 0.78 | KDM1A (0.49) | KMT2AMEN1KDM1AKDM4ETP53 | |
| SCHEMBL9351793 | 0.77 | KDM1A (0.45) | ACHEKMT2ANPSR1KDM1AMAPT | |
| SCHEMBL9105519 | 0.76 | ACHE (0.47) | ACHEKMT2ANPSR1KDM1AKDM4E | |
| SCHEMBL9107670 | 0.76 | ACHE (0.61) | ACHEKMT2AMEN1KDM1APOLB | |
| SCHEMBL9106864 | 0.75 | ACHE (0.58) | ACHEKDM4EHTTPOLBRAD52 | |
| SCHEMBL9351872 | 0.72 | CDK1 (0.42) | KMT2AMEN1KDM1AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897400-A | ENHANCING MEMORY | HOESCHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-01-30 | — | — | US | claimed |
| US-5401749-A | Memory enhancers, cholinergic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-03-28 | — | — | US | disclosed |
| US-4897400-A | ENHANCING MEMORY | HOESCHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-01-30 | — | — | US | disclosed |