Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.40 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9108166 | 0.87 | KMT2A (0.57) | ACHEBCHEPOLBRAD52KMT2A | |
| SCHEMBL9108456 | 0.86 | TACR3 (0.51) | ACHEBCHELMNARAB9ASMN1; SMN2 | |
| SCHEMBL9107713 | 0.84 | ACHE (0.41) | ACHEBCHEPOLBRAD52KMT2A | |
| SCHEMBL9107725 | 0.81 | ACHE (0.58) | ACHEBCHEPOLBRAD52KMT2A | |
| SCHEMBL9103472 | 0.80 | KMT2A (0.60) | ACHEBCHEPOLBRAD52KMT2A | |
| SCHEMBL10468403 | 0.79 | TACR3 (0.53) | POLBRAD52KMT2ALMNARAB9A | |
| SCHEMBL9352687 | 0.77 | RAB9A (0.44) | ACHEPOLBKMT2ALMNARAB9A | |
| SCHEMBL12043394 | 0.75 | BCHE (0.54) | ACHEBCHEPOLBRAD52KMT2A | |
| SCHEMBL9874509 | 0.75 | ACHE (0.67) | ACHE | |
| SCHEMBL9109812 | 0.75 | ACHE (0.56) | ACHEBCHEPOLBRAD52KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401749-A | Memory enhancers, cholinergic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-03-28 | — | — | US | claimed |
| US-5401749-A | Memory enhancers, cholinergic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-03-28 | — | — | US | disclosed |