Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 5/20 | 0.44 |
| ▸ | BCL2L2 | Q92843 | 5/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.43 |
| ▸ | TGM2 | P21980 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL281692 | 0.88 | KMT2A (0.40) | TGM2TRPA1AADATKMT2A | |
| SCHEMBL9107280 | 0.86 | SMN1; SMN2 (0.40) | TGM2KMT2A | |
| SCHEMBL9109123 | 0.80 | BCL2 (0.49) | BCL2BCL2L2MCL1KMT2A | |
| SCHEMBL9105317 | 0.79 | CCKBR (0.39) | TGM2TRPA1AADATKMT2A | |
| SCHEMBL9105927 | 0.78 | GCK (0.45) | KMT2A | |
| SCHEMBL9105660 | 0.77 | BCL2 (0.42) | BCL2BCL2L2MCL1 | |
| SCHEMBL9908080 | 0.77 | GCK (0.41) | — | |
| SCHEMBL9103302 | 0.77 | SMN1; SMN2 (0.41) | BCL2BCL2L2MCL1TRPA1AADAT | |
| SCHEMBL9101953 | 0.77 | GCK (0.66) | KMT2A | |
| SCHEMBL9908079 | 0.77 | KDM4E (0.44) | TGM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142705-A1 | ISATIN AND OXINDOLE COMPOUNDS | KESTER ROBERT FRANCIS (US) | 2012-06-07 | — | — | US | claimed |
| US-20120142705-A1 | ISATIN AND OXINDOLE COMPOUNDS | KESTER ROBERT FRANCIS (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142705-A1 | ISATIN AND OXINDOLE COMPOUNDS | GPR119, INSR, OAT | BCL2 740/4885BCL2L2 535/4885MCL1 3695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.