Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109035 | 0.93 | ACHE (0.48) | ACHEHTR3AHRH4TYMSFABP4 | |
| SCHEMBL9108166 | 0.86 | KMT2A (0.57) | ACHEBCHEPDE5APOLBRAD52 | |
| SCHEMBL9108799 | 0.81 | ACHE (0.55) | ACHEBCHEPOLBRAD52KMT2A | |
| SCHEMBL9106547 | 0.81 | ACHE (0.66) | ACHEBCHEHTR3AHRH4FABP4 | |
| SCHEMBL9352687 | 0.80 | RAB9A (0.44) | ACHEPKMPOLBKMT2A | |
| SCHEMBL9107713 | 0.78 | ACHE (0.41) | ACHEBCHEPOLBRAD52KMT2A | |
| SCHEMBL9108456 | 0.78 | TACR3 (0.51) | ACHEBCHE | |
| SCHEMBL9103472 | 0.78 | KMT2A (0.60) | ACHEBCHEPDE5APKMPOLB | |
| SCHEMBL10848116 | 0.75 | — | — | |
| SCHEMBL9108831 | 0.74 | ACHE (0.60) | ACHEBCHEFABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897400-A | ENHANCING MEMORY | HOESCHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-01-30 | — | — | US | claimed |
| US-5401749-A | Memory enhancers, cholinergic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-03-28 | — | — | US | disclosed |
| US-4897400-A | ENHANCING MEMORY | HOESCHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-01-30 | — | — | US | disclosed |