Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.31 |
| ▸ | FDPS | P14324 | 8/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514939 | 0.80 | LPAR1 (0.50) | LPAR1LPAR3GGPS1FDPS | |
| SCHEMBL9513449 | 0.78 | LPAR1 (0.42) | LPAR1LPAR3GGPS1 | |
| SCHEMBL1527593 | 0.76 | PNP (0.42) | LPAR1LPAR3 | |
| SCHEMBL9110451 | 0.75 | LPAR1 (0.64) | LPAR1LPAR3GGPS1FDPS | |
| SCHEMBL1527573 | 0.73 | PNP (0.40) | LPAR1LPAR3 | |
| SCHEMBL9109027 | 0.72 | LPAR1 (0.61) | LPAR1LPAR3GGPS1FDPS | |
| SCHEMBL9513432 | 0.71 | FAAH (0.46) | GGPS1FDPS | |
| SCHEMBL15114777 | 0.71 | LPAR1 (0.37) | LPAR1LPAR3 | |
| SCHEMBL15114551 | 0.71 | LPAR1 (0.37) | LPAR1LPAR3 | |
| SCHEMBL1527439 | 0.67 | PNP (0.40) | LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338887-B1 | Phosphonoalkylpurine derivatives | MERRELL DOW PHARMA (US) | 1993-12-08 | — | — | EP | disclosed |
| US-4988680-A | Phosphorylase inhibitors, immuno suppressants, parasiticides, antileukemia agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0338887-A1 | Phosphonoalkylpurine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-10-25 | — | — | EP | disclosed |