SCHEMBL9110050

SCHEMBL9110050

CN(C)c1ccc2c(c1)C(c1c(-c3ccccc3)[nH]c3ccccc13)OC2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
MMP13 P45452 1/20 0.41
HTR2A P28223 9/20 0.39
KCNH2 Q12809 5/20 0.38
HTR2C P28335 5/20 0.38
DRD2 P14416 2/20 0.37
HPGD P15428 2/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
KIF11 P52732 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
GUSB P08236 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382857 1.00 MMP2 (0.41) MMP2MMP9MMP8MMP13HTR2A
SCHEMBL9096475 0.91 MMP2 (0.41) MMP2MMP9MMP8MMP13HTR2A
SCHEMBL3881114 0.82 ALDH1A1 (0.50) HTR2AKCNH2HTR2CDRD2HPGD
SCHEMBL30557434 0.82 ALDH1A1 (0.50) HTR2AKCNH2HTR2CDRD2HPGD
SCHEMBL9268997 0.80 ALDH1A1 (0.38) HTR2AKCNH2HTR2CDRD2HPGD
SCHEMBL9100407 0.72 LMNA (0.40) HPGDHTTSMN1; SMN2GAAKDM4E
SCHEMBL10691917 0.71 ALDH1A1 (0.49) HPGDGAAKDM4EMAPT
SCHEMBL1098701 0.69 HPGD (0.43) MMP2MMP9MMP8MMP13HTR2A
SCHEMBL30387132 0.69 HPGD (0.43) MMP2MMP9MMP8MMP13HTR2A
SCHEMBL4597661 0.68 CGAS (0.52) MAPK1HTTMGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112533967-B Oil-in-water droplet type emulsion of active energy ray-curable resin composition and thermosensitive recording material 日本化药株式会社 2023-09-15 CN disclosed
CN-116034036-A Thermosensitive recording material 日本化药株式会社 2023-04-28 CN disclosed
CN-111315841-B Curable organopolysiloxane release agent composition for thermal paper, and thermal recording label sheet 陶氏东丽株式会社 2023-02-21 CN disclosed
US-20210189193-A1 CURABLE ORGANOPOLYSILOXANE RELEASE AGENT COMPOSITION FOR THERMAL PAPER, THERMAL PAPER, AND THERMAL RECORDING LABEL SHEET DOW TORAY CO., LTD. (JP) 2021-06-24 US disclosed
EP-3719096-A1 CURABLE ORGANOPOLYSILOXANE RELEASE AGENT COMPOSITION FOR THERMAL PAPER, THERMAL PAPER, AND THERMAL RECORDING LABEL SHEET Dow Toray Co., Ltd. (JP) 2020-10-07 EP disclosed
CN-111315841-A Curable organopolysiloxane release agent composition for thermal paper, and thermal recording label sheet 陶氏东丽株式会社 2020-06-19 CN disclosed
CN-108430789-B Thermosensitive recording material 日本化药株式会社 2020-03-31 CN disclosed
US-5418206-A High gloss, abrasion resistant, thermosensitive recording element INTERNATIONAL PAPER COMPANY (US) 1995-05-23 US disclosed
EP-0643646-A1 THERMOSENSITIVE RECORDING ELEMENT. INT PAPER CO (US) 1995-03-22 EP disclosed
EP-0609323-A1 THERMOSENSITIVE RECORDING ELEMENT HAVING IMPROVED SMOOTHNESS CHARACTERISTICS. INT PAPER CO (US) 1994-08-10 EP disclosed
EP-0609378-A1 ABRASION RESISTANT, THERMOSENSITIVE RECORDING ELEMENT INTERNATIONAL PAPER COMPANY (US) 1994-08-10 EP disclosed
WO-1993024331-A1 THERMOSENSITIVE RECORDING ELEMENT INTERNATIONAL PAPER COMPANY (US) 1993-12-09 WO disclosed
US-4482378-A BENZOTRIAZOLE DERIVATIVES SOCIETE ANONYME: AUSSEDAT-REY (FR) 1984-11-13 US disclosed