SCHEMBL2113189

SCHEMBL2113189

[CH2]CCCCCC(=O)c1ccccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.51
MAPT P10636 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
LMNA P02545 1/20 0.46
ACHE P22303 1/20 0.45
SGMS1 Q86VZ5 1/20 0.45
SGMS2 Q8NHU3 1/20 0.45
HTT P42858 3/20 0.45
ALDH1A1 P00352 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ATM Q13315 1/20 0.45
HPGD P15428 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
HMGB1 P09429 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6746832 0.93 CYP19A1 (0.54) CYP19A1MAPTTDP1LMNAHTT
SCHEMBL8519711 0.91 CYP19A1 (0.59) CYP19A1MAPTL3MBTL1TDP1LMNA
SCHEMBL8670350 0.91 CYP19A1 (0.59) CYP19A1MAPTL3MBTL1TDP1LMNA
SCHEMBL8672674 0.91 CYP19A1 (0.59) CYP19A1MAPTL3MBTL1TDP1LMNA
SCHEMBL29164312 0.84 HDAC3 (0.61) CYP19A1MAPTL3MBTL1TDP1LMNA
Phenol SCHEMBL9396776 0.84 CYP19A1 (0.62) CYP19A1MAPTL3MBTL1TDP1LMNA
SCHEMBL31661878 0.84 HDAC3 (0.61) CYP19A1MAPTL3MBTL1TDP1LMNA
SCHEMBL1114801 0.84 HDAC3 (0.61) CYP19A1MAPTL3MBTL1TDP1LMNA
SCHEMBL6691190 0.82 HTT (0.67) CYP19A1MAPTLMNAHTTALDH1A1
SCHEMBL6694401 0.82 HTT (0.67) CYP19A1MAPTLMNAHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240173228-A1 COSMETIC COMPOSITION COMPRISING HINOKITIOL CONOPCO, INC., D/B/A UNILEVER (US) 2024-05-30 US disclosed
US-20240058246-A1 LIPO-AMINO ACID ALKYL ESTERS AS SPF BOOSTERS PRODOTTI GIANNI S.R.L. (IT) 2024-02-22 US disclosed
US-20240033189-A1 METHOD FOR PRODUCING A PERSONALIZED COSMETIC PREPARATION BASF SE (DE) 2024-02-01 US disclosed
US-20230372215-A1 CROSSLINKED POLYGLYCEROL ESTERS EVONIK OPERATIONS GMBH (DE) 2023-11-23 US disclosed
US-11807603-B2 Cross-linked polyglycerol esters EVONIK OPERATIONS GMBH (DE) 2023-11-07 US disclosed
US-11793738-B2 Lipo-amino acid alkyl esters as SPF boosters PRODOTTI GIANNI S.R.L. (IT) 2023-10-24 US disclosed
US-20230310295-A1 SUNSCREEN OR DAILY CARE COMPOSITION COMPRISING MICRONIZED METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL BASF SE (DE) 2023-10-05 US disclosed
US-20230310290-A1 SUNSCREEN OR DAILY CARE COMPOSITION COMPRISING MICRONIZED TRIS-BIPHENYL TRIAZINE BASF SE (DE) 2023-10-05 US disclosed
US-20230107458-A1 EMULSIFYING AND TEXTURING COMPOSITION BASED ON STARCHES AND GUMS, FOR COSMETICS ALLIANCE GUM & INDUSTRIES (FR) 2023-04-06 US disclosed
US-20230055814-A1 Process for enzymatically preparing sugar esters and/or sugar alcohol esters EVONIK OPERATIONS GMBH (DE) 2023-02-23 US disclosed
US-8158678-B2 Photoabsorbing, highly conjugated compounds of cyanoacrylic esters, sunscreen compositions and methods of use CPH INNOVATIONS CORP. 2012-04-17 US disclosed
WO-2011086073-A2 WATER-RESISTANT COSMETIC FORMULATIONS COMPRISING A HYDROPHOBICALLY MODIFIED VINYLPYRROLIDONE COPOLYMER BASF SE (DE) 2011-07-21 WO disclosed
US-20100303746-A1 GRINDING AIDES FOR MICRONIZED ORGANIC UV ABSORBERS BASF SE (US) 2010-12-02 US disclosed
US-7713519-B2 Method of quenching electronic excitation of chromophore-containing organic molecules in photoactive compositions HALLSTAR INNOVATIONS CORP. (US) 2010-05-11 US disclosed
US-20100040566-A1 EMULSION RIEMANN TRADING APS 2010-02-18 US disclosed
US-20100028275-A1 Alkyl Benzoate Mixtures COGNIS IP MANAGEMENT GMBH (DE) 2010-02-04 US disclosed
US-20090098076-A1 Method For the Production of a Keratin-Binding Effector Molecule BASF SE (DE) 2009-04-16 US disclosed
US-20090074687-A1 METHOD OF QUENCHING ELECTRONIC EXCITATION OF CHROMOPHORE-CONTAINING ORGANIC MOLECULES IN PHOTOACTIVE COMPOSITIONS HALLSTAR INNOVATIONS CORP. (US) 2009-03-19 US disclosed
US-20080193395-A1 COSMETIC PREPARATION WITH VINYLPYRROLIDONE/ACRYLIC ACID COPOLYMER BEIERSDORF AG (DE) 2008-08-14 US disclosed
US-20060228311-A1 Photoabsorbing, highly conjugated compounds of cyanoacrylic esters, sunscreen compositions and methods of use BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2006-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240033189-A1 METHOD FOR PRODUCING A PERSONALIZED COSMETIC PREPARATION CUTA, NISCH, TYR CYP19A1 14/4885MAPT 1088/4885L3MBTL1 4829/4885
US-11793738-B2 Lipo-amino acid alkyl esters as SPF boosters SLC43A1, CUTA, AADAT CYP19A1 184/4885MAPT 4702/4885L3MBTL1 3381/4885
US-20100303746-A1 GRINDING AIDES FOR MICRONIZED ORGANIC UV ABSORBERS MGLL, GYS2, F12 CYP19A1 1812/4885MAPT 1518/4885L3MBTL1 3857/4885
US-20060228311-A1 Photoabsorbing, highly conjugated compounds of cyanoacrylic esters, sunscreen compositions and methods of use XPA, ERCC4, UNG CYP19A1 762/4885MAPT 1387/4885L3MBTL1 3847/4885
US-20100028275-A1 Alkyl Benzoate Mixtures ACOX3, PAOX, GABBR1 CYP19A1 50/4885MAPT 2135/4885L3MBTL1 2753/4885
US-20090074687-A1 METHOD OF QUENCHING ELECTRONIC EXCITATION OF CHROMOPHORE-CONTAINING ORGANIC MOLECULES IN PHOTOACTIVE COMPOSITIONS CRYAA, CRY2, CRYAB CYP19A1 1127/4885MAPT 3548/4885L3MBTL1 321/4885
US-20240058246-A1 LIPO-AMINO ACID ALKYL ESTERS AS SPF BOOSTERS SLC43A1, CUTA, AADAT CYP19A1 184/4885MAPT 4702/4885L3MBTL1 3381/4885
US-20240173228-A1 COSMETIC COMPOSITION COMPRISING HINOKITIOL MITF, SUV39H2, SUV39H1 CYP19A1 222/4885MAPT 1401/4885L3MBTL1 4436/4885
US-20090098076-A1 Method For the Production of a Keratin-Binding Effector Molecule KRT18, KRTCAP2, CUTA CYP19A1 3796/4885MAPT 2227/4885L3MBTL1 3908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.