Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 4/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | RXRG | P48443 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27537945 | 0.94 | RXRB (0.41) | RXRBTPSAB1RXRARXRGNPC1 | |
| SCHEMBL2089033 | 0.83 | RXRB (0.37) | RXRBRXRARXRGNAAAGRIN2B | |
| SCHEMBL9720050 | 0.81 | TSHR (0.46) | RXRBRXRARXRGNPC1RAB9A | |
| SCHEMBL23472586 | 0.81 | MLNR (0.50) | NPC1RAB9ACA1CA2MLNR | |
| SCHEMBL81351 | 0.81 | RXRB (0.42) | RXRBRXRARXRGNPC1RAB9A | |
| SCHEMBL81619 | 0.81 | RXRB (0.39) | RXRBTPSAB1RXRARXRGNPC1 | |
| SCHEMBL6348778 | 0.81 | TPSAB1 (0.43) | RXRBTPSAB1RXRARXRGCA12 | |
| SCHEMBL11411476 | 0.79 | NPC1 (0.44) | RXRBRXRARXRGNPC1RAB9A | |
| SCHEMBL7122292 | 0.79 | S1PR1 (0.46) | NPC1RAB9AALDH1A1MLNR | |
| SCHEMBL28297053 | 0.79 | MAOA (0.44) | RXRBTPSAB1GRIN2BCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1784226-A | Benzimidazole compounds, compositions containing benzimidazole compounds, and methods of use | MERCK & CO INC (US) | 2006-06-07 | — | — | CN | disclosed |
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |