SCHEMBL9110487

SCHEMBL9110487

CC(COc1[c]cccc1)COC(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.32
SCN4A P35499 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27771397 0.80 FFAR1 (0.40) SCN4A
SCHEMBL4776326 0.80 FFAR1 (0.40) SCN4A
SCHEMBL264457 0.78 POLB (0.37) SCN4A
SCHEMBL19405368 0.78 GPR88 (0.37)
SCHEMBL28785239 0.76 PBRM1 (0.35) SCN4A
SCHEMBL26662211 0.75 SCN4A (0.50) SCN4A
SCHEMBL27673182 0.75 LMNA (0.53) SCN4A
SCHEMBL14237494 0.73 GRM4 (0.33) SCN4A
SCHEMBL2230868 0.71 THRA (0.33)
SCHEMBL11370574 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1114834-A antidiabetic agent OTSUKA PHARMA CO LTD (JP) 1996-01-10 CN disclosed
EP-0670831-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-09-13 EP disclosed
WO-1995009159-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-04-06 WO disclosed