Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978509 | 0.90 | L3MBTL1 (0.40) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL29565483 | 0.90 | L3MBTL1 (0.40) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5644282 | 0.90 | ALDH1A1 (0.39) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL29565080 | 0.88 | ATM (0.41) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL1408896 | 0.88 | ATM (0.41) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL1792470 | 0.86 | MEN1 (0.35) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL29913570 | 0.85 | KDM4E (0.36) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL8978570 | 0.85 | KDM4E (0.36) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5159693 | 0.84 | KDM4E (0.33) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL29565487 | 0.84 | KDM4E (0.33) | KMT2AMAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995016215-A1 | NOVEL SUBSTITUTED NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1995-06-15 | — | — | WO | disclosed |