Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112564 | 0.82 | CTSL (0.54) | PKMTACR1KDM4EMAPTMEN1 | |
| SCHEMBL9234332 | 0.81 | PKM (0.49) | PKMTACR1KDM4EMAPTMEN1 | |
| SCHEMBL9112282 | 0.81 | PKM (0.49) | PKMTACR1KDM4EMAPTMEN1 | |
| SCHEMBL9115060 | 0.80 | SSTR1 (0.57) | TACR1MAPTLMNA | |
| SCHEMBL9110945 | 0.80 | KDM4E (0.46) | PKMTACR1KDM4EMAPTMEN1 | |
| SCHEMBL23551129 | 0.75 | MEN1 (0.55) | PKMKDM4EMAPTMEN1LMNA | |
| SCHEMBL133958 | 0.74 | TACR1 (0.72) | PKMTACR1KDM4EMAPTMEN1 | |
| SCHEMBL29632750 | 0.74 | TACR1 (0.72) | PKMTACR1KDM4EMAPTMEN1 | |
| SCHEMBL839065 | 0.74 | TACR1 (0.72) | PKMTACR1KDM4EMAPTMEN1 | |
| SCHEMBL840121 | 0.74 | TACR1 (0.72) | PKMTACR1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995008550-A1 | ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1995-03-30 | — | — | WO | disclosed |