Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112570 | 0.80 | KDM4E (0.46) | KDM4EKMT2AMEN1POLBPKM | |
| SCHEMBL9110935 | 0.80 | PKM (0.48) | KDM4EKMT2AMEN1POLBPKM | |
| SCHEMBL23551129 | 0.75 | MEN1 (0.55) | KDM4EKMT2AMEN1PKMSMN1; SMN2 | |
| SCHEMBL4471722 | 0.74 | PKM (0.59) | KDM4EKMT2AMEN1PKMSMN1; SMN2 | |
| SCHEMBL9584209 | 0.72 | PKM (0.55) | KDM4EKMT2AMEN1PKMSMN1; SMN2 | |
| SCHEMBL9112564 | 0.71 | CTSL (0.54) | KDM4EKMT2AMEN1PKMALDH1A1 | |
| SCHEMBL9234332 | 0.71 | PKM (0.49) | KDM4EKMT2AMEN1POLBPKM | |
| SCHEMBL1970759 | 0.71 | PKM (0.53) | KDM4EKMT2AMEN1PKMSMN1; SMN2 | |
| SCHEMBL9112282 | 0.71 | PKM (0.49) | KDM4EKMT2AMEN1POLBPKM | |
| SCHEMBL14542028 | 0.69 | HTR2A (0.54) | KDM4EKMT2AMEN1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995008550-A1 | ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1995-03-30 | — | — | WO | disclosed |