Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671426 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MEN1LMNAKMT2AMMP1 | |
| SCHEMBL6830282 | 0.85 | AIMP2 (0.44) | ALDH1A1MEN1KMT2AREN | |
| SCHEMBL9113795 | 0.77 | CTSK (0.46) | MAPTREN | |
| SCHEMBL8683934 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AMMP1MMP2 | |
| SCHEMBL28381301 | 0.73 | ALDH1A1 (0.49) | ALDH1A1MEN1LMNAKMT2AMMP1 | |
| SCHEMBL13956959 | 0.73 | FKBP1A (0.44) | KMT2AKDM4ECA2CA1GAA | |
| SCHEMBL66348 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MEN1LMNAKMT2AMMP1 | |
| SCHEMBL15251698 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MEN1LMNAKMT2AMMP1 | |
| SCHEMBL27416542 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MEN1LMNAKMT2AMMP1 | |
| SCHEMBL67049 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MEN1LMNAKMT2AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995008550-A1 | ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1995-03-30 | — | — | WO | disclosed |