Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIMP2 | Q13155 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 11/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.40 |
| ▸ | CTSE | P14091 | 1/20 | 0.40 |
| ▸ | PGC | P20142 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671426 | 0.85 | ALDH1A1 (0.44) | MEN1KMT2ARENALDH1A1 | |
| SCHEMBL9111024 | 0.85 | ALDH1A1 (0.44) | MEN1KMT2ARENALDH1A1 | |
| SCHEMBL6444798 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6444760 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7385524 | 0.75 | MEN1 (0.61) | MEN1KMT2ARENALDH1A1CTSD | |
| SCHEMBL7317104 | 0.75 | MEN1 (0.61) | MEN1KMT2ARENALDH1A1CTSD | |
| SCHEMBL7331287 | 0.74 | REN (0.63) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7916527 | 0.73 | CA12 (0.48) | ALDH1A1 | |
| SCHEMBL6801263 | 0.73 | CTSS (0.69) | CTSSALDH1A1 | |
| SCHEMBL6802863 | 0.73 | CTSS (0.69) | CTSSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389624-A1 | Phosphorous-containing cysteine and serine protease inhibitors | CEPHALON, INC. (US) | 2004-02-18 | — | — | EP | disclosed |
| EP-0871454-B1 | PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON INC (US) | 2003-11-12 | — | — | EP | disclosed |
| EP-0871454-A4 | — | — | 1998-11-25 | — | — | EP | disclosed |
| EP-0871454-A1 | PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5639732-A | FOR TREATING NERVOUS SYSTEM DISORDERS OR AS ANTIINFLAMMATORY AGENT | CEPHALON, INC. (US) | 1997-06-17 | — | — | US | disclosed |
| WO-1997003679-A1 | PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1997-02-06 | — | — | WO | disclosed |