Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761863 | 0.83 | MMP9 (0.57) | POLBCTDSP1MEN1KMT2AHDAC8 | |
| SCHEMBL8761898 | 0.83 | MMP9 (0.57) | POLBCTDSP1MEN1KMT2AHDAC8 | |
| SCHEMBL1168971 | 0.81 | POLB (0.64) | POLBCTDSP1MEN1KMT2AHDAC8 | |
| SCHEMBL8761845 | 0.81 | MEN1 (0.51) | POLBCTDSP1MEN1KMT2AHDAC8 | |
| SCHEMBL8760756 | 0.81 | POLB (0.53) | POLBCTDSP1MEN1KMT2AHDAC8 | |
| SCHEMBL8761814 | 0.80 | MEN1 (0.57) | POLBCTDSP1MEN1KMT2AHDAC8 | |
| SCHEMBL27518632 | 0.79 | POLB (0.57) | POLBCTDSP1MEN1KMT2AHDAC8 | |
| SCHEMBL27518634 | 0.79 | POLB (0.57) | POLBCTDSP1MEN1KMT2AHDAC8 | |
| SCHEMBL7313409 | 0.78 | POLB (0.55) | POLBCTDSP1MEN1KMT2AHDAC8 | |
| SCHEMBL7313421 | 0.78 | POLB (0.55) | POLBCTDSP1MEN1KMT2AHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995017418-A2 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF L-ASPARTYL-D-α-AMINOALKANOYL-(S)-N-α-ALKYLBENZYL AMIDES USEFUL AS ARTIFICIAL SWEETENERS | THE COCA-COLA COMPANY (US) | 1995-06-29 | — | — | WO | disclosed |