Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 3/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761814 | 0.90 | MEN1 (0.57) | POLBMEN1KMT2ANPY1RNPY5R | |
| SCHEMBL1168971 | 0.84 | POLB (0.64) | POLBMEN1KMT2ACTDSP1MME | |
| SCHEMBL8761898 | 0.83 | MMP9 (0.57) | POLBMEN1KMT2ACTDSP1HDAC8 | |
| SCHEMBL8761863 | 0.83 | MMP9 (0.57) | POLBMEN1KMT2ACTDSP1HDAC8 | |
| SCHEMBL8761845 | 0.81 | MEN1 (0.51) | POLBMEN1KMT2ACTDSP1MME | |
| SCHEMBL9111863 | 0.81 | POLB (0.52) | POLBMEN1KMT2ACTDSP1HDAC8 | |
| SCHEMBL17074050 | 0.80 | METAP2 (0.45) | MMP2MMP3 | |
| SCHEMBL17074049 | 0.80 | METAP2 (0.45) | MMP2MMP3 | |
| SCHEMBL8760779 | 0.78 | GPR88 (0.44) | POLB | |
| Hydrochloric Acid SCHEMBL3367302 | 0.77 | MEN1 (0.56) | POLBMEN1KMT2ANPY1RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286509-A | L-aspartyl-D-α-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as artificial sweeteners | THE COCA-COLA COMPANY (US) | 1994-02-15 | — | — | US | claimed |
| EP-0779296-A2 | D-alpha-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as intermediates for artificial sweeteners | THE COCA-COLA COMPANY (US) | 1997-06-18 | — | — | EP | disclosed |
| WO-1995017418-A2 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF L-ASPARTYL-D-α-AMINOALKANOYL-(S)-N-α-ALKYLBENZYL AMIDES USEFUL AS ARTIFICIAL SWEETENERS | THE COCA-COLA COMPANY (US) | 1995-06-29 | — | — | WO | disclosed |
| US-5286509-A | L-aspartyl-D-α-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as artificial sweeteners | THE COCA-COLA COMPANY (US) | 1994-02-15 | — | — | US | disclosed |