Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.56 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.56 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15156731 | 0.89 | TPSAB1 (0.58) | TPSAB1TPSD1TPSG1MEN1KMT2A | |
| SCHEMBL9112269 | 0.88 | TPSAB1 (0.56) | TPSAB1TPSD1TPSG1MEN1KMT2A | |
| SCHEMBL654289 | 0.81 | RECQL (0.71) | TPSAB1TPSD1TPSG1MEN1KMT2A | |
| SCHEMBL656547 | 0.81 | FKBP1A (0.72) | TPSAB1TPSD1TPSG1MEN1KMT2A | |
| SCHEMBL5072941 | 0.80 | MEN1 (0.78) | TPSAB1TPSD1TPSG1MEN1KMT2A | |
| SCHEMBL13806604 | 0.79 | TPSAB1 (0.58) | TPSAB1TPSD1TPSG1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL211137 | 0.78 | MEN1 (0.76) | TPSAB1TPSD1TPSG1MEN1KMT2A | |
| Cyanide SCHEMBL26699229 | 0.78 | GAA (0.69) | TPSAB1TPSD1TPSG1MEN1KMT2A | |
| SCHEMBL1374133 | 0.76 | NPC1 (0.77) | TPSAB1TPSD1TPSG1MEN1KMT2A | |
| SCHEMBL5942013 | 0.75 | LMNA (0.58) | MEN1KMT2ALMNASYKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |