Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374681 | 0.85 | AKR1B1 (0.48) | LMNASYKMAPK1KDM4EALDH1A1 | |
| SCHEMBL12374684 | 0.85 | KDM4E (0.47) | LMNASYKKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL353914 | 0.85 | MAOA (0.61) | LMNAALOX15PTPN7ACMSDMAPK1 | |
| SCHEMBL4416397 | 0.83 | ALOX15 (0.61) | LMNAALOX15PTPN7ACMSDMAPK1 | |
| SCHEMBL2608055 | 0.82 | PTPN7 (0.63) | LMNAALOX15PTPN7PPARAPPARG | |
| SCHEMBL413254 | 0.82 | LMNA (0.81) | LMNAALOX15PTPN7MAPK1PPARA | |
| SCHEMBL4683688 | 0.80 | CCNB2 (0.65) | LMNAALOX15SYKPTPN7ACMSD | |
| SCHEMBL4683690 | 0.80 | CCNB2 (0.65) | LMNAALOX15SYKPTPN7ACMSD | |
| SCHEMBL3175679 | 0.80 | LMNA (0.54) | LMNAALOX15PTPN7ACMSDMAPK1 | |
| SCHEMBL3175689 | 0.80 | LMNA (0.54) | LMNAALOX15PTPN7ACMSDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2822928-B1 | SUBSTITUTED HETEROCYCLIC ACETAMIDES AS KAPPA OPIOID RECEPTOR (KOR) AGONISTS | Dr Reddys Laboratories Ltd (IN) | 2018-11-14 | — | — | EP | disclosed |
| US-20060073411-A1 | Chemically amplified resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-04-06 | — | — | US | disclosed |
| US-20040191674-A1 | Chemical amplification resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-09-30 | — | — | US | disclosed |
| US-6656660-B1 | Resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-12-02 | — | — | US | disclosed |
| EP-1024406-A1 | Resist composition | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 2000-08-02 | — | — | EP | disclosed |