Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PKLR | P30613 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776938 | 0.77 | MAPT (0.32) | MAPTTP53HTTMEN1LMNA | |
| SCHEMBL5355939 | 0.69 | — | — | |
| SCHEMBL4615662 | 0.69 | F9 (0.30) | — | |
| SCHEMBL289345 | 0.69 | — | — | |
| SCHEMBL346282 | 0.69 | — | — | |
| SCHEMBL29942154 | 0.69 | BACE1 (0.35) | MAPTMEN1LMNAKMT2A | |
| SCHEMBL6964252 | 0.69 | ADRA2A (0.51) | MAPTMEN1LMNAKMT2ANPSR1 | |
| SCHEMBL29527999 | 0.67 | ALDH1A1 (0.37) | MAPTTP53HTTMEN1LMNA | |
| SCHEMBL28754170 | 0.67 | ALDH1A1 (0.37) | MAPTTP53HTTMEN1LMNA | |
| SCHEMBL3503184 | 0.67 | PKLR (0.38) | PKLRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7082268-A | — | — | None | — | — | JP | disclosed |
| JP-H0782268-A | PRODUCTION OF BENZOTHIADIAZOLE DERIVATIVE | PERMACHEM ASIA LTD | 1995-03-28 | — | — | JP | disclosed |