Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534322 | 0.79 | TDO2 (0.31) | — | |
| SCHEMBL23039754 | 0.76 | BAZ1A (0.33) | SMN1; SMN2BAZ1AMAPTMEN1NPC1 | |
| SCHEMBL18912235 | 0.72 | BAZ1A (0.31) | BAZ1A | |
| SCHEMBL23039753 | 0.71 | LMNA (0.46) | SMN1; SMN2LMNAMAPTMEN1NPC1 | |
| SCHEMBL23039755 | 0.68 | NPC1 (0.35) | MAPTMEN1NPC1GAARAB9A | |
| SCHEMBL11684574 | 0.68 | PI4KA (0.34) | SMN1; SMN2LMNAMAPTMEN1NPC1 | |
| SCHEMBL10589771 | 0.67 | BAZ1A (0.36) | SMN1; SMN2BAZ1AMAPTMEN1NPC1 | |
| SCHEMBL10589746 | 0.67 | BAZ1A (0.36) | SMN1; SMN2BAZ1ALMNAMAPTMEN1 | |
| SCHEMBL8874949 | 0.65 | AURKA (0.35) | — | |
| SCHEMBL2359630 | 0.64 | TSHR (0.47) | SMN1; SMN2LMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7082268-A | — | — | None | — | — | JP | disclosed |
| JP-H0782268-A | PRODUCTION OF BENZOTHIADIAZOLE DERIVATIVE | PERMACHEM ASIA LTD | 1995-03-28 | — | — | JP | disclosed |