Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112914 | 0.79 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL9615205 | 0.68 | TDO2 (0.33) | TDO2 | |
| SCHEMBL8874949 | 0.68 | AURKA (0.35) | TDO2 | |
| SCHEMBL21712222 | 0.65 | PI4KA (0.36) | — | |
| SCHEMBL23039755 | 0.63 | NPC1 (0.35) | — | |
| SCHEMBL21596543 | 0.63 | — | — | |
| SCHEMBL15893393 | 0.63 | NPC1 (0.46) | — | |
| SCHEMBL21596542 | 0.63 | BAZ1A (0.33) | — | |
| SCHEMBL23039754 | 0.63 | BAZ1A (0.33) | — | |
| SCHEMBL659651 | 0.63 | MEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348872-B1 | FUSED DIHYDROXYQUINOXALINES AND THEIR USE AS GLUTAMATE ANTAGONISTS | NOVO NORDISK A/S (DK) | 1993-09-29 | — | — | EP | disclosed |
| US-5109001-A | Treating hyperactivity of excitatory neurotransmitters | NOVO NORDISK A/S (DK) | 1992-04-28 | — | — | US | disclosed |
| US-5079250-A | TRICYCLIC HETEROCYCLIC DIOLS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-01-07 | — | — | US | disclosed |
| US-5075306-A | Nervous system, psychological disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| US-5057516-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-10-15 | — | — | US | disclosed |
| US-4977155-A | Nervous system disorders | A/S FERROSAN (DK) | 1990-12-11 | — | — | US | disclosed |
| US-4786739-A | SULFIDING | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0146610-A4 | SUBSTITUTED BENZOPENTATHIEPINS, PROCESS THEREFOR AND INTERMEDIATES. | DU PONT (US) | 1986-02-20 | — | — | EP | disclosed |
| US-4571404-A | PLANT HERBICIDE, FUNGICIDE OR VIRICIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-02-18 | — | — | US | disclosed |
| EP-0146610-A1 | SUBSTITUTED BENZOPENTATHIEPINS, PROCESS THEREFOR AND INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-07-03 | — | — | EP | disclosed |
| WO-1984004921-A1 | SUBSTITUTED BENZOPENTATHIEPINS, PROCESS THEREFOR AND INTERMEDIATES | DU PONT (US) | 1984-12-20 | — | — | WO | disclosed |