Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30388241 | 0.78 | ALDH1A1 (0.41) | HTR2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL25180650 | 0.78 | ALDH1A1 (0.41) | HTR2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL11419089 | 0.73 | SLC6A2 (0.37) | SLC6A2SLC6A4HTR2ACYP2D6NPC1 | |
| SCHEMBL18536393 | 0.73 | HTR2A (0.37) | SLC6A2SLC6A4HTR2ACYP2D6NPC1 | |
| SCHEMBL22731139 | 0.73 | HTR2A (0.37) | SLC6A2SLC6A4HTR2ACYP2D6NPC1 | |
| SCHEMBL24999225 | 0.73 | MAOA (0.41) | SLC6A2SLC6A4HTR2ACYP2D6NPC1 | |
| SCHEMBL3420534 | 0.73 | MAOA (0.41) | SLC6A2SLC6A4HTR2ACYP2D6NPC1 | |
| SCHEMBL3683946 | 0.73 | LMNA (0.39) | SLC6A2SLC6A4HTR2ACYP2D6NPC1 | |
| SCHEMBL3216781 | 0.73 | SLC6A2 (0.40) | SLC6A2SLC6A4HTR2ACYP2D6HTR2C | |
| SCHEMBL5086903 | 0.73 | HTR2A (0.46) | SLC6A2SLC6A4HTR2ACYP2D6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105246876-B | Condensed heterocyclic compound and pest control use thereof | 住友化学株式会社 | 2017-06-16 | — | — | CN | disclosed |
| CN-105530923-A | Aryl ethers and their use | PELOTON THERAPEUTICS INC | 2016-04-27 | — | — | CN | disclosed |
| WO-2008133884-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-11-06 | — | — | WO | disclosed |