Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | GLUL | P15104 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843068 | 0.80 | PGK1 (0.35) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9114706 | 0.76 | FDPS (0.52) | FOLH1 | |
| SCHEMBL8842649 | 0.76 | ALDH1A1 (0.37) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9115882 | 0.75 | FOLH1 (0.42) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9117128 | 0.74 | LAP3 (0.41) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9116738 | 0.73 | FOLH1 (0.41) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9116720 | 0.73 | FDPS (0.55) | — | |
| SCHEMBL31475487 | 0.72 | FOLH1 (0.48) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9115862 | 0.72 | FOLH1 (0.39) | FOLH1NAALAD2GLUL | |
| SCHEMBL9114695 | 0.72 | FOLH1 (0.37) | FOLH1NAALAD2GLUL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995011249-A1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING THEM AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-27 | — | — | WO | disclosed |