Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CPS1 | P31327 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951685 | 0.84 | L3MBTL1 (0.40) | LMNARXFP1PTGS2BCAT2BCAT1 | |
| SCHEMBL8914465 | 0.83 | BCAT1 (0.37) | BCAT2BCAT1GRM8CYP1A2GRM7 | |
| SCHEMBL8899310 | 0.83 | NPSR1 (0.36) | SMN1; SMN2RAB9AGAARXFP1BCAT2 | |
| SCHEMBL24241965 | 0.82 | MAP2K1 (0.35) | RXFP1 | |
| SCHEMBL9114198 | 0.82 | ESR1 (0.40) | RXFP1 | |
| SCHEMBL7562176 | 0.82 | HSD11B1 (0.36) | LMNAGAACYP1A2 | |
| SCHEMBL9338931 | 0.82 | ALDH1A1 (0.34) | LMNAALDH1A1RXFP1MAPT | |
| SCHEMBL7893270 | 0.82 | RXFP1 (0.46) | SMN1; SMN2ALDH1A1RXFP1MAPTHTT | |
| SCHEMBL7557543 | 0.81 | GSK3A (0.46) | SMN1; SMN2LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9114664 | 0.80 | MAOB (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995017096-A1 | HERBICIDAL HALOALKYLURACILS | FMC CORPORATION (US) | 1995-06-29 | — | — | WO | disclosed |
| US-5399543-A | Chemical intermediates for the herbicides also claimed. | FMC CORPORATION (US) | 1995-03-21 | — | — | US | disclosed |