Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9243102 | 0.98 | GHSR (0.37) | GHSRPTGS2PTGS1GCKPTGDR2 | |
| SCHEMBL9118390 | 0.96 | PTGS2 (0.39) | GHSRPTGS2PTGS1GCKPTGDR2 | |
| SCHEMBL9117292 | 0.90 | GHSR (0.37) | GHSRPTGS2GCKALOX5AP | |
| SCHEMBL9116916 | 0.86 | GHSR (0.38) | GHSRPTGS2PTGS1GCK | |
| SCHEMBL9118488 | 0.83 | PTGS2 (0.53) | GHSRPTGS2PTGS1 | |
| SCHEMBL9117225 | 0.81 | PTGS2 (0.50) | PTGS2PTGS1ALOX5AP | |
| SCHEMBL9117616 | 0.81 | PTGS2 (0.53) | GHSRPTGS2PTGS1 | |
| SCHEMBL9119692 | 0.79 | PIK3CD (0.36) | PTGS2PTGS1ALOX5AP | |
| SCHEMBL9242947 | 0.78 | PTGS2 (0.50) | PTGS2PTGS1ALOX5AP | |
| SCHEMBL8389237 | 0.78 | PTGS2 (0.44) | GHSRPTGS2PTGS1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030652-A1 | SUBSTITUTED SPIRODIENES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-11-16 | — | — | WO | disclosed |