Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 15/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820163 | 0.91 | LTA4H (0.55) | LTA4HKDM4EALDH1A1NPSR1RXFP1 | |
| SCHEMBL6820161 | 0.91 | LTA4H (0.55) | LTA4HKDM4EALDH1A1NPSR1RXFP1 | |
| SCHEMBL2179155 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1NPSR1RXFP1NPC1 | |
| SCHEMBL1404234 | 0.82 | LTA4H (0.42) | LTA4HKDM4EALDH1A1RXFP1 | |
| Benzene SCHEMBL6822148 | 0.82 | MMP2 (0.47) | KDM4EALDH1A1NPSR1RXFP1NPC1 | |
| SCHEMBL9115646 | 0.82 | TNIK (0.43) | LTA4HKDM4EALDH1A1NPSR1RXFP1 | |
| SCHEMBL9185732 | 0.80 | ALDH1A1 (0.52) | KDM4EALDH1A1NPSR1RXFP1NPC1 | |
| SCHEMBL6818486 | 0.79 | MMP2 (0.44) | KDM4EALDH1A1NPSR1RXFP1NPC1 | |
| SCHEMBL29687817 | 0.78 | LTA4H (0.70) | LTA4HKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL10908490 | 0.78 | LTA4H (0.70) | LTA4HKDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379925-B1 | A NUCLEIC ACID ENCODING A PROTEIN; THERAPY FOR HEMANGIOMAS, KAPOSI'S SARCOMA, ISCHEMIC DISORDERS AND WOUNDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2002-04-30 | — | — | US | disclosed |
| WO-1998057621-A1 | ANGIOGENIC MODULATION BY NOTCH SIGNAL TRANSDUCTION | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OFNEW YORK (US) | 1998-12-23 | — | — | WO | disclosed |
| US-5089394-A | Neisseria detection system | E-Y LABORATORIES, INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0122023-A1 | Microorganisms detection methods and the separation of agglutinated microorganisms, and a kit for use therein | E-Y LABORATORIES, INC. (US) | 1984-10-17 | — | — | EP | disclosed |
| EP-0122028-A1 | Colorimetric assay for enzymes, diagnostic article therefor and a method for forming such article | E-Y LABORATORIES, INC. (US) | 1984-10-17 | — | — | EP | disclosed |