Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820163 | 1.00 | LTA4H (0.55) | LTA4HKDM4EALDH1A1NPSR1RXFP1 | |
| SCHEMBL7715008 | 0.91 | LTA4H (0.55) | LTA4HKDM4EALDH1A1NPSR1RXFP1 | |
| SCHEMBL2179155 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1NPSR1RXFP1NPC1 | |
| SCHEMBL9115646 | 0.82 | TNIK (0.43) | LTA4HKDM4EALDH1A1NPSR1RXFP1 | |
| SCHEMBL9185732 | 0.80 | ALDH1A1 (0.52) | KDM4EALDH1A1NPSR1RXFP1NPC1 | |
| SCHEMBL23849151 | 0.79 | LTA4H (0.76) | LTA4H | |
| SCHEMBL14544643 | 0.78 | MAPT (0.48) | KDM4EALDH1A1NPSR1RXFP1MEN1 | |
| Hydrochloric Acid SCHEMBL25181404 | 0.78 | LTA4H (0.74) | LTA4H | |
| Benzene SCHEMBL6822148 | 0.78 | MMP2 (0.47) | KDM4EALDH1A1NPSR1RXFP1NPC1 | |
| SCHEMBL14521459 | 0.77 | MAPT (0.46) | KDM4EALDH1A1NPSR1RXFP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |