Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.58 |
| ▸ | CTSB | P07858 | 2/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115688 | 1.00 | CTSL (0.58) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL24095783 | 0.83 | CA5A (0.51) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL26295696 | 0.83 | CA5A (0.51) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL1977017 | 0.82 | CTSL (0.71) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL7715048 | 0.82 | CTSL (0.71) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL1977941 | 0.82 | CTSL (0.71) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL12555462 | 0.82 | CTSL (0.71) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL25494046 | 0.82 | CTSL (0.71) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL13610346 | 0.82 | CTSL (0.71) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL9006092 | 0.82 | CA2 (0.74) | CTSLCTSBCTSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664789-A4 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE. | — | 1995-09-06 | — | — | EP | disclosed |
| EP-0664789-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | Merck & Co., Inc. (a New Jersey corp.) (US) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994000419-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1994-01-06 | — | — | WO | disclosed |