Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.30 |
| ▸ | CDK2 | P24941 | 2/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115124 | 0.89 | KDM4E (0.65) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9116325 | 0.85 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9114485 | 0.81 | HSP90AB1 (0.44) | HDAC6HSP90AA1HSP90AB1 | |
| SCHEMBL7816738 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Famciclovir SCHEMBL8190642 | 0.77 | KDM4E (1.00) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Famciclovir SCHEMBL2949 | 0.77 | KDM4E (1.00) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Famciclovir SCHEMBL29357294 | 0.77 | KDM4E (1.00) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Famciclovir SCHEMBL3932051 | 0.76 | KDM4E (0.98) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL14382185 | 0.76 | KDM4E (0.81) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Famciclovir SCHEMBL7103048 | 0.76 | KDM4E (0.98) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995022330-A1 | ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1995-08-24 | — | — | WO | disclosed |