Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14015374 | 0.72 | CA1 (0.42) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6571405 | 0.71 | RAPGEF4 (0.43) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL18700928 | 0.71 | F2 (0.41) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27447331 | 0.69 | F2 (0.37) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10309404 | 0.68 | FFAR4 (0.57) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27617593 | 0.67 | CA1 (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL17023255 | 0.67 | RAPGEF4 (0.36) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL1074347 | 0.66 | CSNK2A2 (0.42) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL1805293 | 0.65 | CA1 (0.39) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL23788 | 0.64 | CA1 (0.58) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995013284-A1 | ASYMMETRIC HYDROBORATION | ISIS INNOVATION LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |