Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 12/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1047352 | 0.74 | RAPGEF4 (0.39) | RAPGEF4ACHEMAPTGLACA1 | |
| SCHEMBL17023255 | 0.74 | RAPGEF4 (0.36) | RAPGEF4MAPTGLACA1CA2 | |
| SCHEMBL11420240 | 0.73 | RAPGEF4 (0.43) | RAPGEF4ACHEMAPTGLACA1 | |
| SCHEMBL242786 | 0.73 | RAPGEF4 (0.43) | RAPGEF4ACHEMAPTALDH1A1KDM4E | |
| SCHEMBL9116079 | 0.71 | CA1 (0.42) | RAPGEF4MAPTCA1CA2MMP1 | |
| SCHEMBL10798387 | 0.71 | RAPGEF4 (0.41) | RAPGEF4ACHEMAPTALDH1A1KDM4E | |
| SCHEMBL129762 | 0.71 | ACHE (0.57) | RAPGEF4ACHEMAPTALDH1A1LMNA | |
| Phosphine SCHEMBL22634061 | 0.71 | RAPGEF4 (0.41) | RAPGEF4ACHEMAPTALDH1A1KDM4E | |
| SCHEMBL7023644 | 0.69 | RAPGEF4 (0.39) | RAPGEF4ACHEMAPTGLAALDH1A1 | |
| Methylamine SCHEMBL18641330 | 0.69 | RAPGEF4 (0.39) | RAPGEF4ACHEMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1393053-A1 | ION SENSITIVE ELECTRODES BASED ON OXA-AZAMACROCYCLES AS IONOPHORE FOR THE DETERMINATION OF NITRATE, SALICYLATE, OR PERIODATE ANIONS | The Robert Gordon University (GB) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002099409-A1 | ION SENSITIVE ELECTRODES BASED ON OXA-AZAMACROCYCLES AS IONOPHORE FOR THE DETERMINATION OF NITRATE, SALICYLATE OR PERIODATE ANIONS | THE ROBERT GORDON UNIVERSITY (GB) | 2002-12-12 | — | — | WO | disclosed |