Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 10/20 | 0.42 |
| ▸ | CHUK | O15111 | 9/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987784 | 0.82 | KEAP1 (0.56) | KDM4EKEAP1IKBKBCHUKAURKA | |
| SCHEMBL9118277 | 0.80 | KDM4E (0.52) | KDM4EKEAP1IKBKBCHUKPDPK1 | |
| SCHEMBL29502911 | 0.80 | KDM4E (1.00) | KDM4EMETAP2CSNK2A1MYCMEN1 | |
| SCHEMBL108376 | 0.80 | KDM4E (1.00) | KDM4EMETAP2CSNK2A1MYCMEN1 | |
| SCHEMBL4798726 | 0.78 | CYP1A2 (0.40) | KDM4EIKBKBCHUKKMT2A | |
| SCHEMBL28335692 | 0.74 | IKBKB (0.60) | KEAP1IKBKBCHUKPDPK1 | |
| SCHEMBL9117203 | 0.73 | KEAP1 (0.62) | KDM4EKEAP1IKBKBCHUKPDPK1 | |
| SCHEMBL7926770 | 0.72 | HSD17B10 (0.47) | KDM4EKEAP1IKBKBCHUKMYC | |
| SCHEMBL11881146 | 0.71 | KDM4E (0.79) | KDM4EMETAP2CSNK2A1MYCMEN1 | |
| SCHEMBL988102 | 0.69 | NR4A2 (0.44) | KEAP1IKBKBCHUKXDHPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995034658-A1 | MICROBIAL PRODUCTION OF INDOLE-3-ACETIC ACIDS AND SUBSTITUTED ANALOGS THEREOF VIA FERMENTATION | GENENCOR INTERNATIONAL, INC. (US) | 1995-12-21 | — | — | WO | disclosed |